Nicontinamide mononucleotide is supplement that can raise NAD+ levels in cells. It is best taken in the form of a micronized powder which will help increase absorption.
Nicotinamide mononucleotide is a naturally occurring molecule that is needed to make nicotinamide adenine dinucleotide (NAD+), which is essential for many important enzymes to carry out their functions, such as sirtuins and PARPs ³.
During aging, NAD+ levels in our body decline. Nicotinamide mononucleotide can impact various aspects of the aging process ³.
Studies have shown that nicotinamide mononucleotide has a range of potential benefits for human health including improved metabolism and increased energy ².
It has been able to suppress age-associated weight gain, enhance energy metabolism and physical activity, improve insulin sensitivity, improve eye function, improve mitochondrial metabolism and prevent age-linked changes in gene expression ¹.
In mice bred to be diabetic or obese, nicotinamide mononucleotide improved both the action and secretion of insulin. It also protected the mouse heart from ischemia and/or reperfusion injury.
It has restored skeletal muscle in aged mice and slowed cognitive decline in a mouse model of Alzheimer’s disease by improving the survival of neurons, improving energy metabolism, and reducing reactive oxygen species ¹.
Nicotinamide mononucleotide may also help maintain the integrity of the blood-brain barrier ¹. It is likely a good candidate to suppress inflammaging—the increase in inflammation associated with aging—since studies show it lowers adipose tissue inflammation associated with age ¹.
In conclusion, nicotinamide mononucleotide has been shown to have many potential benefits for human health including improved metabolism and increased energy.
It can suppress age-associated weight gain, enhance energy metabolism and physical activity, improve insulin sensitivity, improve eye function, improve mitochondrial metabolism and prevent age-linked changes in gene expression.
It may also help maintain the integrity of the blood-brain barrier and suppress inflammaging. These benefits make nicontinamide mononucleotide an attractive candidate for anti-aging and longevity research.
(1) The Anti-Aging and Longevity Benefits of nicontinamide mononucleotide – NOVOS. https://novoslabs.com/.
(2) The Science Behind nicontinamide mononucleotide for Longevity – Healthy Focus. https://healthyfocus.org/.
(3) The Science Behind nicontinamide mononucleotide –A Stable, Reliable NAD+Activator and Anti-Aging …. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238909/.
(4) Nicotinamide Mononucleotide: Benefits, Side Effects … – Healthline. https://www.healthline.com/health/
(5) The role of nicotinamide mononucleotide in anti-aging, longevity …. https://pubmed.ncbi.nlm.nih.gov/35441939/.
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